Patent filings > APPFT - Patent Applications

Novel RNA Composition and Production Method for Use in iPS Cell Generation

12/15/2022 — , a gene may encode a protein-coding RNA essential for protein/peptide synthesis, such as messenger RNA (mRNA) and its RNA precursors as well as derivatives. In some cases
Scientific studies > MDPI

A Synthetic Biology Approach for Vaccine Candidate Design against Delta Strain of SARS-CoV-2 Revealed Disruption of Favored Codon Pair as a Better Strategy over Using Rare Codons

02/20/2023 — ], selection forces [ 70 ], TpA having mRNA destabilizing effect [ 62 ], higher susceptibility of UpA to cytoplasmic RNase [ 71 ] and evading interferon-inducible protein ZAP and
News > ACCESSWIRE - News

CureVac Welcomes Myriam Mendila as New Chief Development Officer

02/01/2023 — ) is a global biopharmaceutical company in the field of messenger RNA (mRNA) technology, with more than 20 years of expertise in developing, optimizing, and manufacturing
Scientific studies > PubMed Abstracts

Ceruloplasmin deficient mice show changes in PTM profiles of proteins involved in messenger RNA processing and neuronal projections and synaptic processes.

12/30/2022 — show changes in PTM profiles of proteins involved in messenger RNA processing and neuronal projections and synaptic processes B Villadsen  1   2 , C Thygesen  1   2
Scientific studies > PubMed Articles

Analysis of Myocarditis Among 252 Million mRNA-1273 Recipients Worldwide.

02/09/2023 — . Abbreviations: COVID-19, coronavirus disease 2019; mRNA, messenger RNA; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2. Figure 1. Distribution and time to onset
News > CRISPR Medicine News - News

News - UK Medicines Regulator Awards Innovation Passport to Base-Editing Candidate for Heart Disease

02/15/2023 — public health need. VERVE-101 is designed to permanently lower low-density lipoprotein cholesterol VERVE-101 consists of an adenine base editor (ABE) messenger RNA (licensed
Press releases > Businesswire - Health News

Review Highlights Growing Evidence That PharmaJet’s Precision Delivery Devices Improve Nucleic Acid Vaccine Performance

02/23/2023 — vaccines, such as messenger RNA (mRNA), that provide scalability and can be quickly adapted as new variants appear. DNA vaccines are also nucleic acid vaccines. Currently, 250
Scientific studies > MDPI

Full-Length Transcriptome Profiling of Coridius chinensis Mitochondrial Genome Reveals the Transcription of Genes with Ancestral Arrangement in Insects

01/15/2023 — , tRNAs were removed from the primary transcripts, leaving messenger RNA (mRNA) and rRNA transcripts. As a supplement to this model, the “reverse cleavage” model in
Scientific studies > PubMed Articles

Humoral response and safety of the BNT162b2 and mRNA-1273 COVID-19 vaccines in allogeneic hematopoietic stem cell transplant recipients: An observational study.

03/02/2023 — . Only one case of new development of mild chronic GVHD was recorded. Conclusion: Messenger RNA COVID-19 vaccines induce humoral responses in allo-HSCT recipients and
Scientific studies > PubMed Articles

Comment on "Heterologous adenovirus-vector/messenger RNA regimen, humoral response and liver transplant recipients".

12/02/2022 — "Heterologous adenovirus-vector/messenger RNA regimen, humoral response and liver transplant recipients" Pathum Sookaromdee  1 , Viroj Wiwanitkit  2 Affiliations Expand
Press releases > Businesswire - Health News

ReCode Therapeutics Announces Strategic Investment from the Cystic Fibrosis Foundation to Accelerate Development of Novel mRNA Therapy

01/10/2023 — Therapeutics is a genetic medicines company using superior delivery to power the next wave of messenger RNA (mRNA) and gene correction therapeutics. ReCode’s selective organ
News > Toronto Star - Canada

Skin cancer vaccine by Moderna succeeds in combination with Merck drug

12/13/2022 — decades with only limited success, not least because they’re hard to manufacture on a large scale. Moderna’s messenger RNA technology is more flexible than many older
Scientific studies > MDPI

N6-methyladenosine Modification of Noncoding RNAs: Mechanisms and Clinical Applications in Cancer

11/30/2022 — .; Rottman, F. Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells. Proc. Natl. Acad. Sci. USA 1974 , 71, 3971–3975. [ Google Scholar
Scientific studies > PubMed Abstracts

Changes in mRNA and miRNA expression in the prelimbic cortex related to depression-like syndrome induced by chronic social defeat stress in mice.

02/14/2023 — interest. Similar articles Molecular mechanism of reward treatment ameliorating chronic stress-induced depressive-like behavior assessed by sequencing miRNA and mRNA in
News > ACCESSWIRE - News

CureVac Announces Proposed Public Offering of Common Shares

02/07/2023 — ) is a global biopharmaceutical company in the field of messenger RNA (mRNA) technology, with more than 20 years of expertise in developing, optimizing, and manufacturing
Scientific studies > PubMed Abstracts

Review of the current and potential use of biological and molecular methods for the estimation of the postmortem interval in animals and humans.

02/07/2023 — future molecular methods as they pertain to DNA and primarily to messenger RNA degradation for the estimation of the PMI, as well as the use of RNA in aging wounds, aging
Scientific studies > PubMed Abstracts

Astaxanthin treatment ameliorates ER stress in polycystic ovary syndrome patients: a randomized clinical trial.

03/01/2023 — ), CCAAT/enhancer-binding protein homologous protein (CHOP), and X-box-binding protein 1 compared to the placebo group, though the reduction in the messenger RNA (mRNA
Scientific studies > PubMed Abstracts

Assessment of Efficacy and Safety of mRNA COVID-19 Vaccines in Children Aged 5 to 11 Years: A Systematic Review and Meta-analysis.

01/24/2023 — efficacy and safety of messenger RNA (mRNA) COVID-19 vaccines in children aged 5 to 11 years has been emerging. Collecting these data will inform clinicians, families, and
Press releases > Brandeis University - Press Releases

Opinion: Thought mRNA vaccines would end with the pandemic? Think again

12/14/2022 — ? Weissman: In an mRNA vaccine, the mRNA acts as a kind of middleman. In our cells, DNA contains all the codes for the proteins we need to live. The messenger RNA makes a
Scientific studies > PubMed Abstracts

Intra-Exon Motif Correlations as a Proxy Measure for Mean Per-Tile Sequence Quality Data in RNA-Seq.

01/24/2023 — higher and less dependent on the GC content parameters in the IVT-Plasmids messenger RNA (mRNA) selection free RNA-Seq sample (control) than in the other RNA-Seq samples
Scientific studies > PubMed Abstracts

Ultradeep characterisation of translational sequence determinants refutes rare-codon hypothesis and unveils quadruplet base pairing of initiator tRNA and transcript.

02/03/2023 — individually account for 53% and 20% of variance in translation, respectively, and show conclusively that, contrary to a common hypothesis, tRNA abundance does not explain
Scientific studies > PubMed Abstracts

Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis.

02/17/2023 — ;1829(3-4):376-84. doi: 10.1016/j.bbagrm.2012.11.004. Epub 2012 Nov 28. Biochim Biophys Acta. 2013. PMID: 23201230 Review. Regulation of tRNA synthesis by the general
Scientific studies > MDPI

Identification of Key Differentially Expressed mRNAs, miRNAs, lncRNAs, and circRNAs for Xp11 Translocation Renal Cell Carcinoma (RCC) Based on Whole-Transcriptome Sequencing

03/15/2023 — on the tumor tissues (RCC) and their matching adjacent normal tissues (Normal). Subsequently, we applied differential analysis of messenger RNA (mRNA), miRNA, lncRNA, and
News > MIT News (Biomechanics) - News

Scientists illuminate a hidden regulator in gene transcription

01/23/2023 — messenger RNA (mRNA) — which delivers its genetic blueprints to the cell’s protein-making machinery. Now researchers at MIT and the Howard Hughes Medical Institute (HHMI
Scientific studies > PubMed Abstracts

tRNA-derived small RNA, 5'tiRNA-Gly-CCC, promotes skeletal muscle regeneration through the inflammatory response.

02/09/2023 — = 0.0009; IL-10, P = 0.0007; IL-13, P = 0.0008) and the mRNA expression of M2 markers (TGF-β1, P = 0.0016; ARG1, P = 0.0083). Flow cytometry showed that 5'tiRNA-Gly
Scientific studies > PubMed Abstracts

The 5'-3' mRNA Decay Pathway Modulates the Plant Circadian Network in Arabidopsis.

11/23/2022 — : journals.permissions@oup.com. Similar articles Circadian control of messenger RNA stability. Association with a sequence-specific messenger RNA decay pathway. Lidder P, Gutiérrez RA
News > Biopharma Dive - News

Moderna, becoming a buyer, acquires a synthetic biology specialist

01/04/2023 — -old company was able to swiftly develop an effective coronavirus vaccine within months of the onset of the pandemic. Pfizer and partner BioNTech also used mRNA technology
Scientific studies > MDPI

Oral Administration of Chaetoceros gracilis—A Marine Microalga—Alleviates Hepatic Lipid Accumulation in Rats Fed a High-Sucrose and Cholesterol-Containing Diet

03/16/2023 — review. Front. Nutr. 2021 , 8, 685165. [ Google Scholar ] [ CrossRef ] Yu, Y.C.; Han, J.M.; Kim, S. Aminoacyl-tRNA synthetases and amino acid signaling. Biochim. Biophys
Scientific studies > PubMed Abstracts

The coordinated regulation of early meiotic stages is dominated by non-coding RNAs and stage-specific transcription in wheat.

01/30/2023 — outstanding questions about meiosis. We conducted a meiotic stage-specific analysis of messenger RNA (mRNA), small non-coding RNA (sncRNA) and long intervening/intergenic non
Clinical trials > Clinical Trials - New studies

Evaluation of the Impact of the Anti COVID-19 Vaccination Campaign Addressed to the Employees of an Italian Hospital.

03/17/2023 — vaccine for preventing coronavirus disease 2019 (COVID-19) in people from the age of 18 years. BNT162b2 contains tozinameran, a messenger RNA (mRNA) molecule with
Scientific studies > DOAJ

as an Independent Prognostic Marker and Therapeutic Target for Nicotine-Related Oral Carcinoma

03/04/2023 — significant decrease in cell viability in SERPINE1-si- lenced cells compared with the control cells. mRNA, messenger RNA; GAPDH, glyceral- dehyde-3-phosphate dehydrogenase; NC
News > Toronto Sun - Canada

Moderna says RSV vaccine 84% effective at preventing symptoms in older adults

01/18/2023 — its experimental messenger RNA vaccine for respiratory syncytial virus (RSV) was 83.7% effective in a late-stage trial at preventing at least two symptoms, such as cough
News > The Scientist - News

Transfer RNAs Have a Surprising Role in Breast Cancer Growth

01/19/2023 — continue to look into the mechanism by which this polarized expression of tRNAs occurs. “If we can figure out how this tRNA polarization happens,” says Tavazoie, “we could perhaps develop an approach to controlling metastatic disease.” Keywords:
Scientific studies > DOAJ

Impact of homologous and heterologous boosters in neutralizing antibodies titers against SARS-CoV-2 Omicron in solid-organ transplant recipients

03/14/2023 — , Avery RK, Tobian AAR, Massie AB, Segev DL, et al. Immunogenicity of a single dose of SARS-CoV-2 messenger RNA vaccine in solid organ transplant recipients. JAMA (2021) 325
Patent filings > APPFT - Patent Applications


01/05/2023 — “DNA.fwdarw.(transcription).fwdarw.mRNA (messenger RNA).fwdarw.(translation) protein”. For example. RNA-Seq (RNA sequencing) using a next-generation sequencer can reveal the
Scientific studies > PubMed Articles

MicroRNA-143-3p Inhibits Wilms' Tumor Cell Growth By Targeting the Ras/Raf/MEK/ERK Pathway.

03/02/2023 — apoptosis. Moreover, k-Ras, a unique oncogene, was confirmed as a direct target of miR-143-3p, and k-Ras messenger RNA (mRNA) expression was increased in WT tissues and
Scientific studies > PubMed Articles

Do plants drive translation reinitiation to dodge nonsense-mediated decay?

01/02/2023 — . - PMC - PubMed Show all 22 references MeSH terms Nonsense Mediated mRNA Decay* Actions Search in PubMed Search in MeSH Add to Search Protein Biosynthesis
News > Nanowerk - News

Nanotechnology-based mRNA vaccines: From the fight against COVID-19 to cancer immunotherapy and HIV vaccines

01/16/2023 — ( Nanowerk Spotlight ) COVID-19 is a game changer for both nanomedicine and nucleic acid-based vaccines. Just two years ago, there were no licensed messenger RNA (mRNA
Scientific studies > PubMed Abstracts

IARA: a complete and curated atlas of the biogenesis of spliceosome machinery during RNA splicing.

03/02/2023 — . 2017. PMID: 27465259 Review. Mechanistic insights into precursor messenger RNA splicing by the spliceosome. Shi Y. Shi Y. Nat Rev Mol Cell Biol. 2017 Nov;18(11):655-670
News > The Medical News

New method for capturing moments during protein translation

02/10/2023 — which underscores that the method really does capture the intermediate pep-tRNA pool during translation. ", says Prof. Taguchi when quizzed on the significance of their
Scientific studies > PubMed Abstracts

Benefits of co-translational complex assembly for cellular fitness.

03/15/2023 — .74255. Elife. 2022. PMID: 35357307 Free PMC article. Multimodal cotranslational interactions direct assembly of the human multi-tRNA synthetase complex. Khan K, Long B
Scientific studies > MDPI

Ranpirnase (OKG-0301), a Novel Ribonuclease, Demonstrates Antiviral Activity against Adenovirus in the Ad5/NZW Rabbit Ocular Replication Model

12/07/2022 — extraordinary conformational stability [ 12 ]. Within the cell, transfer RNA (tRNA) is the main target of ranpirnase leaving ribosomal RNA (rRNA) and messenger RNA (mRNA
Scientific studies > PubMed Abstracts

Arabidopsis DXO1 activates RNMT1 to methylate the mRNA guanosine cap.

01/14/2023 — CiteCollectionsDisplay options Display options Format AbstractPubMedPMID Abstract Eukaryotic messenger RNA (mRNA) typically contains a methylated guanosine (m7G) cap, which
Scientific studies > PubMed Abstracts

The expression of anti-aging protein Klotho is increased during neural differentiation of bone marrow-derived mesenchymal stem cells.

01/28/2023 — -specific genes at messenger RNA (mRNA) on days 7 and 14 of differentiation using quantitative real-time PCR. In addition, Klotho status at protein level was evaluated by
Scientific studies > PubMed Abstracts

A Single Dose of BNT162b2 Messenger RNA Vaccine Induces Airway Immunity in Severe Acute Respiratory Syndrome Coronavirus 2 Naive and Recovered Coronavirus Disease 2019 Subjects.

12/20/2022 — Messenger RNA Vaccine Induces Airway Immunity in Severe Acute Respiratory Syndrome Coronavirus 2 Naive and Recovered Coronavirus Disease 2019 Subjects Emanuela Martinuzzi  1
Press releases > Oregon Health & Science University - News

No, COVID-19 vaccines aren’t gene therapy

01/06/2023 — , experts say. The shots from Pfizer and Moderna use messenger RNA, or mRNA, to instruct the body to create a protein from the coronavirus. The Johnson & Johnson vaccine
Scientific studies > PubMed Abstracts

Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung.

11/29/2022 — polymeric formulations for inhalable messenger RNA delivery to the lung Laura Rotolo #  1 , Daryll Vanover #  1 , Nicholas C Bruno #  2 , Hannah E Peck  1 , Chiara Zurla
Scientific studies > PubMed Abstracts

Prognosis of Myocarditis Developing After mRNA COVID-19 Vaccination Compared With Viral Myocarditis.

12/14/2022 — Background: Association between messenger RNA (mRNA) COVID-19 vaccines and myocarditis has aroused public concern over vaccine safety. Objectives: The goal of this study was
Securities filings > Edgar - 6-K

6-K - CureVac N.V. (0001809122) (Filer)

02/08/2023 — the field of messenger RNA (mRNA) technology, with more than 20 years of expertise in developing, optimizing, and manufacturing this versatile biological molecule for
Scientific studies > PubMed Abstracts

Safety of COVID-19 vaccines in multiple sclerosis: A systematic review and meta-analysis.

02/02/2023 — independent of the type of administered SARS-CoV-2-vaccine (p for subgroup differences = 0.7 for messenger RNA (mRNA), inactivated virus, and adenovector-based vaccines
Press releases > Medical News Today - News

Personalized mRNA cancer vaccines: When might they become available?

01/12/2023 — expedite time to approval and commercial availability,” she explained. mRNA vaccines mRNA stands for “messenger RNA,” and it works by translating “messages” from DNA to
Scientific studies > DOAJ

The Protective Role of Nrf2 in Renal Tubular Cells in Oxidised Low-Density Lipoprotein-Induced Fibrosis

03/19/2023 — used for the reverse-transcription (RT) PCR were as follows: 5;-GGTGTGCTCAACAGCCTTATC-3; and 5;-TTATGGCAACCTTGCTTATG-3; for detecting rat CD36 messenger RNA (mRNA), 5
Scientific studies > PubMed Abstracts

Genome-wide identification of Kanamycin B binding RNA in Escherichia coli.

03/17/2023 — verify the binding with Kanamycin B in vitro. Kanamycin B and ibsC mRNA was analysed by chemical probing. Conclusions: The results will provide biochemical evidence and
Scientific studies > PubMed Abstracts

An old friend with a new face: tRNA-derived small RNAs with big regulatory potential in cancer biology.

02/10/2023 — CW, Kuo KC, Waalkes TP, Borek E. tRNA breakdown products as markers for cancer. Cancer. 1979;44:2120–3. Shi J, Zhang Y, Tan D, Zhang X, Yan M, Zhang Y, et al. PANDORA
Scientific studies > PubMed Abstracts

Targeting RNA:protein interactions with an integrative approach leads to the identification of potent YBX1 inhibitors.

01/19/2023 — to significantly interfere with the binding of messenger RNA (mRNA) to YB-1 in cells. One of our leads is an FDA-approved poly(ADP-ribose) polymerase 1 (PARP-1) inhibitor
Scientific studies > PubMed Articles

MiR-29a-3p: a potential biomarker and therapeutic target in colorectal cancer.

03/02/2023 — precursor miR-29a-3p, DGCR8 The double-stranded RNA-binding protein, mRNA Messenger RNA, 3’UTRs 3’Untranslated regions, RISC MiRNA-induced silencing complex Fig. 3 miR-29a-3p
Scientific studies > PubMed Abstracts

Cinnamaldehyde Induces the Expression of MicroRNA-1285-5p and MicroRNA-140-5p in Chondrocytes to Ameliorate the Apoptosis and Inflammatory Response.

02/15/2023 — reverse transcriptase polymerase chain reaction was performed to measure miR-1285-5p, miR-140-5p, IL-20, and high-mobility group box 1 (HMGB1) messenger RNA (mRNA) expression
Press releases > McGill University - Press releases

Three McGill researchers rank high in Québec Science's "Discoveries of the Year"

01/12/2023 — Cancer Centre and their research team made the Québec Science list for their discovery of the key element in the control of messenger ribonucleic acid (Messenger RNA or
Scientific studies > PubMed Articles

Systemic lupus erythematosus myocarditis after COVID-19 vaccination.

02/02/2023 — : Dadas las justificaciones patogénicas, se debe considerar la asociación entre lupus eritematoso sistémico (LES) y miocarditis. Keywords: BNT162B2 messenger RNA; COVID-19
Scientific studies > PubMed Abstracts

Effectiveness of Messenger RNA-based Vaccines During the Emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant.

12/20/2022 — Clin Infect Dis Actions Search in PubMed Search in NLM Catalog Add to Search . 2022 Dec 19;75(12):2186-2192. doi: 10.1093/cid/ciac325. Effectiveness of Messenger RNA
Scientific studies > MDPI

A High-Throughput Assay for In Vitro Determination of Release Factor-Dependent Peptide Release from a Pretermination Complex by Fluorescence Anisotropy—Application to Nonsense Suppressor Screening and Mechanistic Studies

01/27/2023 — .; Toropygin, I.Y.; Shuvalov, A.; Egorova, T.; Alkalaeva, E. Recognition of 3′ nucleotide context and stop codon readthrough are determined during mRNA translation
Scientific studies > MDPI

Central Retinal Vein Occlusion in a Young Woman with Diabetes and Hypertension after mRNA-Based COVID-19 Vaccination—A Case Report and Brief Review of the Literature

02/05/2023 — , 459–461. [ Google Scholar ] [ CrossRef ] Sugihara, K.; Kono, M.; Tanito, M. Branch Retinal Vein Occlusion after Messenger RNA-Based COVID-19 Vaccine. Case Rep. Ophthalmol
Press releases > Businesswire - Health News

Alnylam Announces U.S. Food and Drug Administration (FDA) Acceptance of Supplemental New Drug Application for ONPATTRO® (patisiran) for the Treatment of the Cardiomyopathy of ATTR Amyloidosis

02/21/2023 — RNAi therapeutic platform, function upstream of today’s medicines by potently silencing messenger RNA (mRNA) – the genetic precursors – that encode for disease-causing or
News > Trib Live

Dispelling the myths: A look at what didn't happen this week, Oct. 2

10/07/2022 — , referred to as a double helix. RNA is closely related to DNA, and one type, called messenger RNA or mRNA, sends instructions to the cell for different purposes. The mRNA in the
Scientific studies > PubMed Abstracts

CircLPAR1 Promotes Neuroinflammation and Oxidative Stress in APP/PS1 Mice by Inhibiting SIRT1/Nrf-2/HO-1 Axis Through Destabilizing GDF-15 mRNA.

01/17/2023 — unknown. Memory performance of APP/PS1 mice was assessed by Morris water maze test. Expression of circLPAR1 and indicated messenger RNA (mRNA) in mouse brain tissues or/and SH
Scientific studies > PubMed Abstracts

A blood mRNA panel that differentiates Alzheimer's disease from other dementia types.

01/08/2023 — , Salathia NS, Brewer JB et al (2020) Noninvasive characterization of Alzheimer’s disease by circulating, cell-free messenger RNA next-generation sequencing. Sci Adv. https
News > BioPharm International - News

Achieving High Yields in Upstream Processing of Plasmids

03/07/2023 — plasmids is rising dramatically as large numbers of messenger RNA (mRNA) vaccines and viral-vector-based therapeutics advance through clinical trials toward approval and
Scientific studies > PubMed Articles

Deletion of adipocyte prohibitin 1 exacerbates high-fat diet-induced steatosis but not liver inflammation and fibrosis.

12/02/2022 — an HFD. Values represent mean ± SEM. HFD, high‐fat diet; mRNA, messenger RNA; PHB1, prohibitin‐1. **p < 0.01 FIGURE 2 Adipocyte‐specific deletion of Phb1 reduces… FIGURE
Press releases > Businesswire - Science News

Alnylam Pharmaceuticals Reports Fourth Quarter and Full Year 2022 Financial Results and Highlights Recent Period Activity

02/23/2023 — healthcare professional. GIVLAARI works by specifically reducing elevated levels of ALAS1 messenger RNA (mRNA), leading to reduction of toxins associated with attacks and
Scientific studies > PubMed Abstracts

Enabling Genetic Code Expansion and Peptide Macrocyclization in mRNA Display via a Promiscuous Orthogonal Aminoacyl-tRNA Synthetase.

01/12/2023 — diversity and provide structural novelty in mRNA display libraries through a heterocycle forming macrocyclization.
Press releases > Businesswire - Health News

Strand Therapeutics Announces Series A1 Bringing Total Round to US$97 Million

11/28/2022 — & Co-Founder, Strand Therapeutics. “The idea behind Strand and programmable mRNA in cancer, is to stimulate an immune response against the tumor using messenger RNA. With
Scientific studies > PubMed Articles

Eosinophil-rich linear IgA bullous dermatosis induced by mRNA COVID-19 booster vaccine.

01/02/2023 — eosinophil-rich linear IgA bullous disease (LABD) following the administration of a messenger RNA COVID-19 booster vaccine. A 66-year-old man presented to the emergency
Scientific studies > PubMed Articles

Cross-sectional associations of maternal PFAS exposure on SARS-CoV-2 IgG antibody levels during pregnancy.

02/16/2023 — Receipt of the BNT162b2 Messenger RNA COVID-19 Vaccine During the Second Trimester of Pregnancy. Kugelman N, Nahshon C, Shaked-Mishan P, Cohen N, Sher ML, Gruber M, Marom
Scientific studies > PubMed Articles

Effects of the BTN162b2 mRNA COVID-19 vaccine in humoral and cellular immunity in patients with chronic lymphocytic leukemia.

02/02/2023 — messenger RNA COVID-19 vaccine was evaluated in 44 CLL patients comprising 20 treatment-naïve, 14 under treatment with ibrutinib and 10 in follow-up after completion of
Scientific studies > PubMed Abstracts

Persons with HIV Develop Spike-Specific Lymph Node Germinal Center Responses following SARS-CoV-2 Vaccination.

02/14/2023 — : 10.1111/imr.13088. Epub 2022 Jun 11. Immunol Rev. 2022. PMID: 35689434 Free PMC article. Review. Immunogenicity and clinical features relating to BNT162b2 messenger RNA
Scientific studies > PubMed Abstracts

Differential expression of m5C RNA methyltransferase genes NSUN6 and NSUN7 in Alzheimer's disease and traumatic brain injury.

01/18/2023 — DNA methylation writers DNMT1, DNMT3A and DNMT3B messenger RNA (mRNA) and a decrease in the reader UHRF1 mRNA in AD samples across three brain regions whilst the DNA
Scientific studies > DOAJ

A deep look into the storm: Israeli multi-center experience of coronavirus disease 2019 (COVID-19) in patients with autoimmune inflammatory rheumatic diseases before and after vaccinations

03/14/2023 — December 2020, the IMH launched a national campaign to vaccinate the population with 2 doses of BNT162b2 (Pfizer-BioNTech) messenger RNA (mRNA) anti-SARS-CoV-2 vaccine, given 3
Scientific studies > PubMed Articles

Circular RNAs: implications of signaling pathways and bioinformatics in human cancer.

03/03/2023 — likely to function as an miR sponge and to positively regulate target mRNA translation. circRNAs containing binding motifs for RBPs might sponge these proteins and regulate
Scientific studies > PubMed Abstracts

Heterologous prime-boost immunization with ChAdOx1-S and BNT162b2: reactogenicity and immunogenicity in a prospective cohort study.

03/02/2023 — (messenger RNA [mRNA]-1273 [Moderna, Cambridge, Massachusetts, USA]; n = 139) vaccination were asked to participate when receiving their second dose. Reactogenicity was
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